Observational {{label}}

Study of Gene Polymorphisms Involved in the Metabolism and Action of Vitamin D in Amyotrophic Lateral Sclerosis

Please note: All trial information reflects the latest data available from the sponsor on ClinicalTrials.gov and other public databases. However, these sources may occasionally be outdated or inaccurate. For the most current information, we recommend contacting the trial sponsor or sites directly.

Overview

Intervention or Drug Name

Sponsor

Trial Status

Phase

Randomization

Trial Duration

Route of Administration

Genetic Target

Repurposed Drugs

Approved by FDA

Approved outside USA

Is a supplement

Details

Enrollment Criteria

Time since symptom onset

Vital Capacity (FVC or SVC)

Approved Medications

Registry Listing

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Purpose

This is a case-control study performed on a biological collection. The polymorphisms present on a pre-defined list of genes will be studied for 400 Amyotrophic Lateral Sclerosis (sporadic type) DNA samples and 400 control DNA samples.

What participation looks like

Eligibility criteria

Inclusion Criteria:
- The primary inclusion criterium is the same for that of the parent biological
collection, i.e. the patients fulfill requirements for probable or definite
Amyotrophic Lateral Sclerosis as defined by revised international criteria (Brooks
et al 2000).
- Additionally, included patients were followed-up by doctors at the University
Hospital of Montpellier, thus enabling verification of Amyotrophic Lateral Sclerosis
criteria over time.
Exclusion Criteria:
- The patient has a familial form of Amyotrophic Lateral Sclerosis (autosomic dominant
or recessive types) with or without a mutation of one of the 3 genes known to be
responsible for familial forms (SOD1, TARDBP, FUS). See Bender (1998).

Locations

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Location Contact: {{location.Contact.Name}} {{location.Contact.Name}} Phone: {{location.Contact.Phone}}

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